I-95 Colleton Co. collision details: 16 vehicles, 10 hospitalized, 2 dead

YEMASSEE, Sc. (WTOC) - [UPDATE as of 7/23/2025]: Wednesday, the South Carolina Highway Patrol said they are investigating two collisions from Tuesday afternoon in Colleton County.

SCHP says the first collision involved three vehicles, one of the three was a commercial motor vehicle.

One person was taken to the hospital following this collision.

Shortly after, a second collision involving 13 vehicles, happened at the same location.

Six of the vehicles involved in the second collision were commercial motor vehicles. According to SCHP, the 13-vehicle collision sent nine people to surrounding hospitals and resulted in two deaths.

SCHP reported that southbound lanes on I-95, at mile marker 41 closed for around 11 hours while traffic was diverted to an alternate route.

The South Carolina Highway Patrol said they are investigating this crash.

[ORIGINAL STORY]: The South Carolina Highway Patrol reported a fatal accident involving multiple vehicles at around 4:30 p.m. on Tuesday, shutting down Interstate 95 for nearly 12 hours.

Details are limited at this time, but they reported a multi-vehicle fatal collision in the late afternoon on I-95 southbound near mile marker 41, which is past Highway 21 before entering Hampton County.

SCHP reported the major interstate was reopened at around 2:30 a.m. on Wednesday.

PREVIOUS COVERAGE: South Carolina Highway Patrol investigating fatal multi-vehicle crash in Colleton County, I-95 southbound closed